بررسی تأثیر کاربرد پلی وینیل پیرولیدون (PVP) درترکیب با کلرهگزیدین در ایجاد رنگ دانه خارجی روی سطح دندان

Background and purpose: Chlorhexidine (CHX) is still considered the gold standard anti-plaque agent. The main disadvantage of chlorhexidine is its taste, and staining. Improvements of these disadvantages are time consume. This study was to determine if polyvinylpyrrolidone (PVP) could be added to chlorhexidine rinses to maintain efficacy and reduce staining. Materials and methods: This study divided to in vivo and in vitro.The in vivo was randomized, double blind study, and 40 patients with moderate to severe inflammation enrolled to study. The patients undergone dental polishing before the study. In case study and control used e Chlorhexidine + polyvinylpyrrolidone Chlorhexidine mouth wash for 2 weeks respectively. Plaque index (PI) and gingival index (GI), bleeding index (BI), and stain index were assessed before and after the intervention. The glass block and spectrophotometry was used to examine the staining intensity of each mouthwash in In vitro study. The data in SPSS and statistical methods were analyzed by Wilcoxon Signed Ranks Test. Results: PI, GI, BI, stain index difference between base line of Chlorhexidine + polyvinyl pyrrolidone and Chlorhexidine mouthwash group was not significant, But the amount of interference between the two groups was significant difference (P=0.006, 0.007, 0.042 respectively). Final severity of body and gingiva between base line of Chlorhexidine + polyvinylpyrrolidone and Chlorhexidine mouthwash group was significant (P<0.05). Final extent of body and gingiva between base line of two groups was significant (P<0.05). Conclusion: 0.2% concentration of Chlorhexidine and 5% PVP concentration in clinical practice to decrease side effect of Chlorhexidine but maintain Chlorhexidine effect